CORDIS Project
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This project investigates the link between DNA damage and chronic inflammation, aiming to develop a non-immunogenic therapeutic strategy for metabolic diseases and neurodegeneration. The approach allows therapeutic agents to cross the blood-brain barrier, addressing significant health challenges associated with inflamm…
DNA damage triggers the activation of innate immune signaling leading to chronic inflammation and the premature onset of e.g. rheumatoid arthritis, diabetes, metabolic diseases and neurodegenerative disorders in man.
Based on our ERC consolidator program DeFiNER, we recently discovered that persistent DNA damage triggers the innate immune system stimulating broad inflammatory and antiviral immune countermeasures that lead to chronic inflammation and the premature onset of severe metabolic compli…
FOUNDATION FOR RESEARCH AND TECHNOLOGYHELLAS
IDRYMA TECHNOLOGIAS KAI EREVNAS
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