CORDIS Project
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The INFLAMAM project investigates the role of specialized cellular structures in microglia related to Alzheimer's disease. By exploring lipid metabolism and immune signaling, it aims to uncover mechanisms that could lead to new therapeutic targets for managing the disease.
Alzheimer’s disease (AD) is an irreversible neurodegenerative condition affecting 50 million people worldwide.
Despite intense research, the pathological mechanisms of AD are still unclear.
Many genetic loci robustly associated with AD code for proteins that are preferentially or exclusively expressed in microglia, supporting a causal role of microglia as key players in disease initiation and progression.
Microglia are brain-resident immune cells that, upon activation, reorganize their cellular…
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
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Switzerland, Fribourg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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