CORDIS Project
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This project investigates the NLRP3 inflammasome, a key component of the immune system that detects infections and tissue damage. It aims to uncover the molecular mechanisms regulating NLRP3 activation, which is implicated in various chronic inflammatory diseases.
The innate immune system protects the host from infections, detects and repairs tissue damage and functions to maintain tissue homeostasis.
Several families of signaling receptors can recognize microbial substances or altered host molecules and orchestrate a coordinated inflammatory response.
Inflammasomes are signaling platforms that control proteolytic activation of highly proinflammatory cytokines of the IL-1β family and thus, are relevant for infection control and numerous inflammatory condi…
UNIVERSITATSKLINIKUM BONN
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