CORDIS Project
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This project aims to develop new in vitro models to study host-microbe interactions in the human gut, focusing on the bacterium Helicobacter pylori and Norovirus. Using organoids derived from adult stem cells, the project seeks to better understand the host's response to these microorganisms.
The mucosal surfaces of the human stomach and gut are in constant contact with bacteria and viruses.
This encompasses the often mutually beneficial relationships with commensals as well as encounters with pathogens.
The study of host-microbe interactions is hampered by a lack of suitable model systems: many bacteria or viruses cannot be cultured or existing models do not sufficiently recount the human disease.
This project aims at the development of new in vitro models and the subsequent charact…
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
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