CORDIS Project
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This project develops a theoretical framework to understand how cells coordinate during embryonic development despite noise. It focuses on how cells process various types of information to make fate decisions, using computational models and experimental systems.
Embryonic development relies on the ability of multi-cellular systems to collectively coordinate the establishment of precise spatial patterns of cell fates.
An inevitable obstacle to such coordination is intrinsic noise at the single-cell level, which constrains the amount of information accessible to cells for fate decisions.
While such information was often considered to be encoded in overall concentrations of extracellular signals, it is becoming increasingly clear that cells use a much broa…
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