CORDIS Project
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INN-TIME investigates how tumors exploit circadian rhythms to evade immune responses. By studying the interaction between cancer and the body's internal clock, the project aims to uncover new strategies to combat cancer by disrupting these tumor-supportive mechanisms.
Circadian rhythms (CRs) are the biological response to the periodic rotations of the Earth, and allowfundamental adaptations of organisms to a changing environment.
CRs are molecularly controlled in every cellby a set of transcriptional factors that control, and are influenced by, core biological processes includingmetabolic, immune, and proliferative.My previous studies established, for the first time, that innate immune cells regulate the circadian physiologyof tissues, including the susceptib…
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