CORDIS Project
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This project explores the dynamics of neutrophils, key immune cells, during inflammation. It aims to uncover the molecular mechanisms that regulate neutrophil behavior, particularly during the resolution phase of immune responses, to inform therapeutic strategies for inflammatory diseases.
Neutrophils are essential effector cells of the innate immune response.
Intravital microscopy studies have recently changed our perspective on neutrophil tissue dynamics.
They revealed swarm-like migration patterns in several models of inflammation and infection:
Neutrophil populations show strikingly coordinated behavior with phases of highly directed chemotaxis and clustering at local sites of tissue damage.
My previous work established that neutrophils self-amplify this swarming response by a…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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