CORDIS Project
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This project focuses on developing new sodium channel blockers for imaging and treating neurological conditions. By synthesizing novel compounds and using advanced imaging techniques, it aims to enhance understanding of nerve function and provide potential drug candidates for pain therapy.
Voltage gated sodium channels (NaVs) are the primary transmembrane proteins underlying fast electrical communication in neurons of the peripheral and central nervous system (PNS and CNS).
Being such an integral part of neuronal signaling, they are implicated in a number of severe diseases that have a major impact on human society.
However, drugs and established therapies targeting NaVs are rare due to common off-target effects.
Therefore, new NaV-blockers will be developed and used for in vivo i…
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United States, Stanford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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