CORDIS Project
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InsideChromatin seeks to understand how the spatial organization of genomic DNA affects gene function. By developing advanced computational models, the project aims to reveal the mechanisms of nucleosome interactions and their influence on chromatin structure, bridging the gap between genome characteristics and biologi…
Reading the genome is one thing – finding out how it functions, is something else altogether.
The next big challenge to understand gene behaviour is deciphering (a) how the genome is organized in space and (b) how this organization influences its function.
Inside Eukaryotic cells, genomic DNA is packed together with proteins into a remarkable structure known as chromatin.
Nucleosomes, the building blocks of chromatin, interact with each other to enable high-density packaging.
Our understanding o…
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