CORDIS Project
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The project investigates how human herpesvirus 6 (HHV-6) maintains its genome during latency and reactivation, utilizing advanced technologies for live-cell imaging and genome editing. It aims to identify factors involved in these processes and develop new therapeutic strategies to eliminate the virus from infected cel…
Herpesviruses cause serious diseases in humans and animals.
After initial lytic infection, herpesviruses establish a quiescent (latent) infection, which allows their persistence in the host for life.
We and others recently identified a novel mechanism that allows maintenance of the genome of certain herpesviruses during latency, by integrating their complete genetic material into host telomeres.
One of these viruses is human herpesvirus 6 (HHV-6) which is associated with seizures, encephalitis,…
FREIE UNIVERSITAET BERLIN
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