CORDIS Project
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This project investigates the interactions between adipocytes and immune cells in white adipose tissue during obesity. It aims to understand how these interactions, influenced by the gut microbiome, contribute to metabolic dysfunction and chronic inflammation.
Obesity affects hundreds of millions of people worldwide and poses a major burden on global health and economy.
Immune cells residing in white adipose tissue (WAT) have recently been highlighted as important factors contributing to metabolic dysfunctions during obesity, which is characterized by chronic low-grade inflammation of fat depots.
The yet unresolved interplay between adipocytes and immune cells in the WAT niche represents a major challenge to any rational interference into the metaboli…
WEIZMANN INSTITUTE OF SCIENCE
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