CORDIS Project
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This project investigates the genetic and lifestyle factors influencing glycaemia, type 2 diabetes, and coronary heart disease. By analyzing gene-lifestyle interactions, it aims to uncover genetic determinants that contribute to disease progression and identify individuals at higher risk, thereby informing prevention s…
Genome-wide association studies (GWAS) for complex traits, including glycaemia, type 2 diabetes (T2D) and coronary heart disease (CHD) have been successful in identifying genetic variants associated with those phenotypes.
However, they explained only a small proportion of the estimated heritability.
Possible reasons include the interplay between genetics and lifestyle determinants, small-effect variants, structural variations and the difficult to characterize non-coding functional variants that…
Institut de Recerca Biomedica Catalunya Sud (IRBCatSud)
FUNDACIO INSTITUT D'INVESTIGACIO SANITARIA PERE VIRGILI (IISPV)
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