CORDIS Project
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This project investigates a novel signaling pathway, galectin1/HOXA5, that regulates brain tumor stem cells in glioblastoma. By targeting these cells, the research aims to develop new therapeutic strategies to improve outcomes for patients suffering from this aggressive brain cancer.
Glioblastoma (GBM) is the most common malignant primary brain tumour in adults.
The current standard of care is surgical resection of GBM tumours followed by chemotherapy and ionizing radiation (IR).
Despite these intense efforts, GBM tumours remain incurable and the median survival rate of GBM patients remains only ~15 months.
This dismal clinical outcome underscores the urgent need for novel therapeutic strategies for GBM.
At the cellular level, GBM tumours contain a rare population of self-re…
UNIVERSITE DE BORDEAUX
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