CORDIS Project
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This project investigates how Mycobacterium tuberculosis survives within macrophages, aiming to develop new strategies to eliminate the bacteria. It employs advanced microscopy and genetic screening to identify crucial genes and compounds that can disrupt the bacteria's persistence and promote effective treatment again…
Tuberculosis, caused by Mycobacterium tuberculosis is still a major threat to global health.
Because the treatment of an infected individual requires more than six months of chemotherapy, compliance is low, which can result in the development of multidrug resistant (MDR-TB) strains.
New drugs and new targets are needed to combat MDR-TB. A critical feature of the Mycobacterium tuberculosis bacillus is its ability to survive and even replicate within macrophages, making these host cells an ideal n…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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