CORDIS Project
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This project explores the biology of bacterial spores, focusing on their structure and behavior during dormancy and germination. By studying Bacillus subtilis, it aims to uncover insights that could lead to better strategies for combating spore-forming pathogens.
When triggered by nutrient limitation, the Gram-positive bacterium Bacillus subtilis and its relatives enter a pathway of cellular differentiation culminating in the formation of a dormant cell type called a spore, the most resilient cell type known.
Bacterial spores can survive for long periods of time and are able to endure extremes of heat, radiation and chemical assault.
Remarkably, dormant spores can rapidly convert back to actively growing cells by a process called germination.
Consequentl…
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