CORDIS Project
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This project investigates the role of the p63 protein in prostate cancer development, focusing on its impact on prostate stem cells. Using advanced biological techniques, the research aims to identify key genes and mechanisms that could be targeted for future cancer therapies.
Cancer results from genetic and epigenetic changes that cause uncontrolled proliferation of cells.
Central to this process are changes in the expression of tumor suppressor genes or oncogenes. P53 is one of the best-characterized tumor suppressor genes, whose expression is lost or mutated in approximately 50% of human cancers. P63 is a member of the p53 gene family that plays critical roles in epithelial cell proliferation and homeostasis, through regulation of cellular senescence and stem cell…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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