CORDIS Project
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This project aims to develop diaryliodonium salts for bioconjugation chemistry. It focuses on creating versatile reagents that can be used in the synthesis of multifunctional protein nucleic acids for drug delivery applications.
This proposal details a plan for the development of diaryliodonium salts as a versatile reagent class for bioconjugation (click) chemistry.
Iodonium salts have a number of desirable properties: they are simple to make and stable to air and moisture, yet display a diverse array of reactivity patterns.
If these reactivity patterns can be adapted to tolerate biologically relevant systems, then they would be a valuable addition to the bioconjugation compendium.
This proposal outlines the first s…
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