CORDIS Project
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This research focuses on a new type of pancreatic cell, islet-associated mesenchymal cells, which are crucial for maintaining the function of insulin-producing beta-cells. The project aims to explore their role in diabetes, particularly Type 2 diabetes, and their potential as a therapeutic target.
Glucose homeostasis relies on tightly controlled release of insulin by pancreatic beta-cells.
Diabetes, characterized by increased blood glucose levels, is a chronic disease now reaching epidemic proportions.
The most common form of this disease is Type 2 diabetes (T2D), which was previously regarded as a disease of insulin resistance.
However, work over the past decadehad shifted this paradigm by implicating beta-cell failure as a key factor in this disease.
Despite major progress, the cellular…
TEL AVIV UNIVERSITY
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