CORDIS Project
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This project aims to understand how cells sense and respond to their mechanical environment, particularly endothelial cells. By manipulating biochemical and mechanical parameters in vitro, it seeks to reveal how these factors influence cell behavior and contribute to various diseases.
Cells have the extraordinary ability to regulate their morphology, functions and fate to minimal changes in the extracelullar microenvironment.
Through multi-protein, cell-matrix adhesions they are able to recognize and respond not only to the chemical diversity of the extracellular matrix (ECM), but also to its physical and topographical features.
Mechanical and structural cues encoded in the ECM have an essential role in healthy tissue function where contractility, spreading and proliferation…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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