CORDIS Project
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This project investigates the mechanisms of nuclear organization in eukaryotic cells, focusing on the behavior of Cajal bodies during stress. It aims to understand how molecular signals influence gene expression and nuclear architecture, which is crucial for developing new diagnostic and treatment strategies for diseas…
The nucleus contains distinct sub-compartments, the composition and localisation of which change during normal physiological processes, or in response to stress or disease.
The molecular stimuli that provoke these changes, and their effects on gene expression are not well characterised.
This proposal aims to further define the mechanisms that underlie nuclear organisation, which is fundamentally important to most eukaryotic cell-types.
Moreover, as there are many diseases linked with distinct ch…
UNIVERSITY OF DUNDEE
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