CORDIS Project
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This project investigates the role of Junctional Adhesion Molecule-A in breast cancer, exploring its potential as a therapeutic target. It aims to test the efficacy of combining JAM-A antagonists with existing breast cancer treatments.
Breast cancer is the most common female malignancy, and a leading cause of death.
Although molecular technologies have led to new therapeutic targets for breast cancer, much remains to be done to reduce its societal and economic impact.
This project focuses on an emerging cancer drug target – Junctional Adhesion Molecule-A (JAM-A), an adhesion protein that Dr Hopkins (Supervisor;
RCSI) and others have implicated in breast cancer.
This proposal centres around recent data suggesting that JAM-A con…
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