CORDIS Project
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This project investigates the role of KDM4 demethylases in human embryonic development. By studying these enzymes, it aims to understand how they affect embryonic cell competency and plasticity, which is crucial for addressing pregnancy-related disorders.
During the first two weeks of human development, the embryo will generate sequentially progenitors of the extraembryonic membranes that will form the supportive tissues of the embryo proper.
Impairments of their development have been linked to pregnancy diseases such as preterm birth.
Human embryonic cells differ from mice by their remarkable plasticity, which allows them to generate extraembryonic lineages during a protracted period of time.
The mechanism extending human embryonic cells compete…
KATHOLIEKE UNIVERSITEIT LEUVEN
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