CORDIS Project
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This project investigates methods to prevent the progression of melanoma by targeting senescent melanocytes, which can re-proliferate and lead to cancer. It employs whole-transcriptome analysis and gene silencing techniques to identify and validate molecular components that support the survival of these cells, aiming t…
Melanoma is the most aggressive type of skin cancer, and its spread to distal tissues is often a death sentence.
Immunotherapies have led to increased survival rates but they are extremely expensive and efficient for approximately only 25% of patients.
Therefore research into new methods to prevent or arrest the progression of melanoma is urgently needed.
Nevi are pigmented lesions on skin which consist of a clonal mass of melanocytes in a state of proliferative arrest termed ‘senescent’.
Thi…
UNIVERSITAIR MEDISCH CENTRUM GRONINGEN
ACADEMISCH ZIEKENHUIS GRONINGEN
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