CORDIS Project
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This project focuses on understanding the role of specific microRNAs in the development of non-small cell lung cancer driven by KRAS mutations. By investigating these microRNAs in both mouse models and human cell lines, the project aims to identify potential therapeutic targets for treating this prevalent cancer type.
Lung cancer is the leading cause of death by cancer in Europe.
Non-small cell lung cancer (NSCLC) represents about 80% of total lung cancers. KRAS is the most commonly mutated oncogene in NSCLC, found in over 20% of patients.
Since KRAS mutations are directly responsible for NSCLC, KRAS represents a relevant target to prevent NSCLC development.
Yet, efforts to develop therapeutic inhibitors have failed for over 20 years, what represents an unmet clinical need in NSCLC.
Thus, it is critical to id…
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
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