CORDIS Project
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This project focuses on improving the synthesis of organo-boron compounds for use in carbon-carbon bond formation reactions, particularly Suzuki cross coupling. It aims to reduce reliance on expensive palladium catalysts by developing new iron-based catalysts and utilizing unique electrophilic borocations to enhance re…
Carbon-carbon bond formation is arguably the most important reaction in synthetic chemistry, exemplified by the award of five noble prizes.
The most recent Nobel prize was awarded for the development of palladium catalysed cross coupling, of which Suzuki cross coupling is the most widely applied version in industry and academia and utilizes organo-boronates (RB(OR)2) as the nucleophilic component.
The aims of this project are; (i) to simplify the synthesis of organo-boron compounds that are util…
THE UNIVERSITY OF MANCHESTER
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