CORDIS Project
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This project focuses on developing a novel treatment for enteric infections, specifically targeting rotavirus and Clostridium difficile. By engineering Lactobacillus bacteria to produce specific antibody fragments, the project aims to provide rapid passive immunity in at-risk populations, potentially through food or dr…
Enteric infections remain a major cause of morbidity and mortality globally, accounting for an estimated 2 millions deaths each year.
Effective preventive and therapeutic interventions are not yet available for many etiological agents of diarrheal diseases.
Furthermore, even where vaccines are available, the lag time needed to induce an immune response can be critical in epidemic situations.
We have developed a model system in which Lactobacillus, a GRAS microorganism, can be transformed with…
KAROLINSKA INSTITUTET
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Estonia, Tartu
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Wageningen
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
Netherlands, Leiden
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
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