CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the dynamic architecture of protein complexes, focusing on the COP9 signalosome, which plays crucial roles in cell-cycle progression, DNA repair, and apoptosis. By employing advanced mass spectrometry and various biological techniques, the aim is to uncover the complex's structural organizatio…
80% of the proteome exists in complexes or large macromolecular assemblies.
It is accepted that revealing the structure of these protein complexes is a key towards mechanistic understanding of cellular processes.
Yet, this might not be sufficient; a higher level of complexity probably exists and protein complexes may not be static and uniform in form and function as thought. A protein complex may actually represent an ensemble of compositionally distinct entities with functional versatility.
My…
WEIZMANN INSTITUTE OF SCIENCE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
