CORDIS Project
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This project focuses on improving gene-regulatory models in systems biology by identifying hidden variables that enhance predictions. Utilizing a Bayesian framework, it aims to refine models of embryonic stem cell differentiation, linking biological information with advanced statistical methods to better understand cel…
In systems biology, we aim at deriving gene-regulatory or signaling models based on multivariate readouts, thereby generating predictions for novel experiments.
However any model only approximates reality, leaving out details or other types of regulation.
Here I ask why a given model fails to predict a set of observations with acceptable accuracy and how to refine the model using this experimental knowledge.
This resembles a question from signal processing, namely the blind identification of hid…
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
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