CORDIS Project
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This project investigates how different Leishmania parasite species influence the migration of infected macrophages, which is crucial for understanding the spread of leishmaniasis. By analyzing macrophage behavior in various experimental setups, the research aims to uncover mechanisms that could lead to new treatments…
Leishmania parasites, a threat to 350 million people worldwide, are transmitted by sand flies and reside predominantly intracellularly in macrophages.
Leishmania species can remain local (cutaneous leishmaniasis) or spread throughout the tissue and body (mucocutaneous/visceral leishmaniasis).
This is the difference between a mild illness or a deadly disease, and the fundamental mechanisms behind these different clinical manifestations are largely unknown.
As Leishmania parasites seem immobile fo…
JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
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