CORDIS Project
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This project focuses on understanding the genetic mutations in Mycobacterium leprae, the bacteria causing leprosy. It aims to identify mutations linked to drug resistance and host immune response, which could enhance treatment strategies for this chronic infection.
Leprosy is a multiform infection caused by Mycobacterium leprae, an uncultivable bacLeprosy is a slow and chronic infection caused by Mycobacterium leprae.
Recent advances in the next generation sequencing offer a new possibility to study the physiopathology of M. leprae, an uncultivable bacteria on anexic media.
In 2018, the comparative analysis of 154 M. leprae genomes from 25 countries identified three hypermutated genes including two (ribD and fadD9) probably associated with drug-resistant a…
SWISS TPH SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE
SCHWEIZERISCHES TROPEN UND PUBLIC HEALTH INSTITUT
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United States, Fort Collins
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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