CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This research focuses on the role of L-selectin, an adhesion receptor in leukocytes, in their migration during infections. By studying the phosphorylation of L-selectin, the project aims to identify new proteins that regulate leukocyte functions, which could lead to new treatments for inflammatory diseases.
Leukocytes protect humans from pathogens.
During episodes of infection, leukocytes leave the blood circulation and migrate to sites in the body where they mount a response against pathogens.
In order for leukocytes to migrate, they must adhere to endothelial cells which cover blood vessels.
Such adhesion allows them to migrate along the endothelial layer, pass though endothelial junctions, and reach tissues.
Excessive migration of leukocytes is a characteristic of inflammatory and auto-immune di…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
