CORDIS Project
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This project aims to create a bacterial strain, LIFE-19, that uses only 19 amino acids for protein synthesis, challenging the conventional understanding of life's building blocks. By engineering a minimal genome, it seeks to explore the limits of biological systems and contribute to synthetic biology.
This proposal aims to construct a bacterial strain LIFE-19 which relies solely on 19 amino acids to build all its proteins.
While all living cells known to human beings produce proteins from the same 20 coded amino acids, the study of origins of life imply that earlier cells may have functioned with a smaller alphabet.
This is thought-provoking in the present biological context, wherein each of the 20 serves a distinct and vital role.
Although many scientists have engaged in theoretical exercise…
UNIVERZITA KARLOVA
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