CORDIS Project
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This study examines the relationship between neuronal activity in specific brain regions and movement control in Parkinson's disease. It aims to enhance understanding of gait initiation and postural adjustments to inform treatment strategies.
Parkinson disease (PD) is the most common movement disorder.
Dysfunction of basal ganglia circuits in PD leads to characteristic motor deficits including bradykinesia, with hypometria and reduced EMG activity, tremor, and frequently gait disorders with start hesitation or freezing of gait (FOG) associated with increased falling.
On the one hand, there is a large literature on the postural adjustments during gait initiation and the biomechanics of ongoing gait in healthy and patient populations.…
INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE
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