CORDIS Project
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This project utilizes natural DNA markers to trace cell lineages in human brain development, addressing challenges in studying human tissues. It aims to uncover the cellular processes involved in brain formation and related disorders.
Organisms develop through cell divisions generating clones that progressively organize to form different tissues.
This process can be visualized as a cell phylogeny by lineage tracing.
In order to track cell lineages, each cell division has to be permanently and uniquely marked.
In model systems, this is done by genome editing.
In humans this is not applicable, which has historically made impossible to accurately study cell phylogenies.
Very recently, however, studies showed that human tissues c…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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France, PARIS 15
Type: Research institute
Activity type: Research Organisations
SME: No
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