CORDIS Project
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This project explores the origins of cell membranes by investigating prebiotic chemistries that could lead to diverse lipid compositions. The research aims to connect early biological processes with non-enzymatic chemistry to understand cellular evolution.
The origin of cell membranes is a major unresolved issue in evolution.
Evolutionary biology points to the existence of primitive cells with compositionally diverse membranes that could actively participate in genetic and metabolic processes.
However, the assumption that such lipid diversity is dependent upon enzymatic chemistry has generated models comprising compositionally minimal membranes (binary or ternary mixtures of short-chain fatty or phosphatidic acids) that passively host genetic or m…
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