CORDIS Project
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This project investigates how the structural integrity of the nucleus affects aging, focusing on the role of nuclear lamina and lipids. It aims to understand the molecular interactions that contribute to nuclear function during healthy aging.
Aging is a major risk factor for many human pathologies.
At a time when we are living longer than ever before, untangling the mechanisms of this biological deterioration is absolutely critical if we aim at providing a better quality of life for aging individuals.
The loss of nuclear integrity, and the consequent defects in nuclear mechanics, is already among widely considered hallmarks of aging.
In mammalian cells, the structural properties of the nucleus are maintained by the nuclear lamina (NL…
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
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