CORDIS Project
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This research develops chemical probes to analyze protein lipidation networks in cancer cells. The goal is to identify mechanisms that can be targeted for chemotherapy, combining organic synthesis, proteomics, and cell biology.
This project aims to develop chemical probes and technologies that will enable for the first time high-throughput analysis and exploration of the complex biological networks involved in protein lipidation.
These chemical tools will be applied to mapping the changes in lipidation that occur in the proliferation and survival of cancer cells, with the ultimate objective of identifying and validating cellular mechanisms that can be targeted for future chemotherapy.
The proposed work is multidiscipli…
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