CORDIS Project
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This project investigates the role of lipid transfer proteins in lipid metabolism by analyzing their effects in cell lines using advanced systems biology techniques. The goal is to uncover how these proteins influence cellular pathways and organelles, enhancing our understanding of non-vesicular lipid transport.
Cellular membranes of eukaryotic cells vary in their lipid composition, which allows segregation of diverse biological processes and specific enrichment of signaling, enzymatic and structural proteins.
Differential enrichment of lipids in different membranes stems from compartmentalized synthesis and degradation of lipids, but also from lipid transport between membranes.
Lipid transfer proteins (LTPs) facilitate non-vesicular lipid transport through aqueous spaces, and their dysfunction can lead…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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