CORDIS Project
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This project aims to develop a non-invasive imaging method to accurately measure liver fibrosis and its progression, addressing the limitations of current techniques. By targeting specific cell markers associated with fibrogenesis, the technology will enhance risk assessment and facilitate the testing of antifibrotic t…
Chronic liver disease can progress to cirrhosis, with death due to liver failure and cancer.
Cirrhosis prevalence in the EU is 0.5%-1%.
However, development of therapies that prevent progression to cirrhosis is hampered by the lack of a sensitive, non-invasive method to quantify fibrosis or fibrosis progression (fibrogenesis).
Liver biopsy 1) is risky, 2) shows high sampling variability, and 3) is too insensitive to assess fibrosis progression in clinical studies.
Conventional radiological imagi…
UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ
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JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Germany, Mainz
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Hannover
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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