CORDIS Project
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This project investigates the interactions between inflammatory cells and epithelial cells in the context of liver cancer, specifically hepatocellular carcinoma. By mapping changes in the inflammatory microenvironment, the research aims to identify molecular mechanisms that drive cancer progression and potential therap…
The link between inflammation and cancer is now established, yet the underlying molecular mechanisms are unresolved.
As tumors progress, they modulate inflammatory cells towards a pro-tumorigenic phenotype.
We have shown that inflammatory cells reciprocate by sculpting the parenchymal epithelial cells. I hypothesize that these reciprocal interactions lie at the heart of the link between inflammation and cancer.Hepatocellular carcinoma (HCC), one of the deadliest tumors, is a prototype of inflamm…
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