CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates lipid nanoparticles for RNA delivery, focusing on overcoming endosomal entrapment. It employs innovative in vitro techniques to study LNP interactions with membranes and aims to enhance the efficacy of gene delivery systems.
Lipid nanoparticles (LNPs) are promising for RNA delivery, yet their effectiveness is hindered by endosomal entrapment post cellular uptake, limiting their therapeutic potential.
The challenge lies in the inadequate understanding of the endosomal escape mechanism.
This project aims to comprehensively replicate endosomal escape in vitro, employing three objectives to explore LNP interactions with membranes and RNA translocation.
Objective 1 focuses on understanding the impact of pH and LNP formul…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
