CORDIS Project
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This project investigates the role of the FOXP1 gene in diffuse B-cell lymphomas, aiming to understand its impact on cancer progression. By analyzing human samples and a transgenic mouse model, the research seeks to identify therapeutic targets for improved cancer diagnosis and treatment.
FOXP1 (Forkhead box-P1) is a winged-helix transcription factor that has been demonstrated to be expressed in a subset of activated B-cell type (ABC) diffuse B-cell lymphomas (DLBCLs).
Strong FOXP1 expression appears to have an additive adverse role in the pathogenesis and clinical behavior of ABC-DLBCL.
We believe that a better understanding of the molecular impact of FOXP1 deregulation in DLBCL will help us to improve the correct stratification of cancer patients as a prerequisite for acute dia…
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
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