CORDIS Project
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This study explores the natural products from the marine cyanobacterium Lyngbya majuscula and its associated bacteria, aiming to identify compounds with potential therapeutic applications. It focuses on the biosynthesis mechanisms of these compounds to enhance sustainable production for drug discovery.
The filamentous marine cyanobacterium, Lyngbya majuscula (order Oscillatoriales) is a prolific source of modular natural products, some of which have shown promise for the treatment of cancer, diabetes, HIV and Alzheimers disease.
However, the failure to grow its axenic cultures (because of the lack of the nifH gene) suggests that obtaining the natural products from the cyanobacterium in sustainable yields is enigmatic.
My investigations into the Kenyan L. majuscula molecular diversity establish…
UNIVERSITY OF NEWCASTLE UPON TYNE
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