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This project investigates the role of Lynx proteins in modulating nicotinic acetylcholine receptors, which are involved in various neurological functions and lung physiology. It aims to characterize Lynx3's function and its potential link to lung diseases.
Tobacco use is the leading preventable cause of death in the world.
Nicotine, which is the addictive ingredient of tobacco, exerts its addictive effect through nicotinic acetylcholine receptors (nAChRs) in the central nervous system (CNS).
Besides mediating nicotine addiction, nAChRs have been implicated in Alzheimer’s disease, Parkinson’s disease, learning and memory, autism, anxiety disorders, depression, cell motility and cellular adhesion.
Lynx1 has recently been identified as a modulator of…
BILKENT UNIVERSITESI VAKIF
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