CORDIS Project
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This project develops innovative human monoclonal antibodies to combat snakebite envenoming, a serious health issue in low and middle-income countries. By utilizing advanced antibody engineering and phage display selection, it aims to create cost-effective and versatile antivenoms that can neutralize multiple snake tox…
Snakebite envenoming is a Neglected Tropical Disease (NTD) that each year affects 2.5 million victims and kills >100,000, unless they are treated with antivenom.
Conventional antivenoms, derived from immunized animals, inflict serum sickness and anaphylaxis in patients, and are costly to manufacture.
Monoclonal human antibodies with special toxin-binding properties that are sensitive towards regulation by their microenvironment (e.g. pH), which may be discovered using phage display selection, ma…
TECHNICAL UNIVERSITY OF DENMARK DTU
DANMARKS TEKNISKE UNIVERSITET
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