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The MAGIX project investigates how cell type compositions influence organ functions, using mucociliary epithelia as a model. By exploring developmental mechanisms, it aims to link variations in cell types to physiological properties, with implications for understanding diseases affecting millions.
Cell type compositions determine tissue morphologies and functions, are adapted during evolution, and their changes cause diseases.
However, we do not understand how cell type compositions can be controlled and modified to predictively achieve different organ functions.
The goal of the MAGIX project is to understand the developmental mechanisms controlling cell type compositions, and to mechanistically link variations of cell type compositions to physiological properties of tissues in developmen…
UNIVERSITAETSKLINIKUM FREIBURG
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