CORDIS Project
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This project investigates the enzymes involved in DNA replication and repair using advanced micromanipulation techniques. By developing new magnetic tweezers, it aims to observe enzymatic activity at a single base resolution, enhancing our understanding of DNA processes.
We propose to investigate the enzymes responsible for DNA replication and repair in micromanipulation experiments with a resolution of a single base.
The detailed mechanism by which DNA is synthesized base after base and the coordination of the enzymes involved in this process are not fully understood.
We shall develop new magnetic tweezers using lithographic techniques associated with evanescent field detection to address these issues.
We shall build arrays of these devices working in parallel,…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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Spain, Barcelona
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
THE PENNSYLVANIA STATE UNIVERSITY
United States, University Park
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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