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MalChemAtlas aims to uncover the communication mechanisms of the malaria parasite, Plasmodium falciparum, by studying its chemical signaling with host cells. The project seeks to identify compounds that could inhibit parasite growth and improve strategies for malaria treatment.
Malaria is the most life-threatening parasitic disease in humans.
Invasion of the malaria parasite, Plasmodium falciparum (Pf), into the blood circulation rewires the harmonious networking between the resident cells.
Until recently, Pf was not thought to be able to communicate when nested within infected human red blood cells (RBCs).
However, we and others have laid the foundations of Pf communication via extracellular vesicles.
We now hypothesize that in order to survive in the hostile host env…
WEIZMANN INSTITUTE OF SCIENCE
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