CORDIS Project
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This project investigates the molecular mechanisms of early mammalian development, focusing on the establishment of polarity in embryos. It employs innovative techniques like lentivirus-based screening and single-cell RNA amplification to identify key genes and their functions, aiming to enhance understanding of embryo…
Early mammalian development is a unique process creating an extraembryonic structure.
Despite its importance for understanding mammalian development and direct relevance to clinical practice, the mechanism underlying polarity establishment in the mammalian embryo has long been elusive.
One of the major obstacles is the lack of description in molecular terms, since very few genes are known to specify the early lineages.
Our recent studies provide a conceptual basis, suggesting that the mechanism…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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