CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project aims to explore the differences between normal and cancer mammary stem cells, focusing on the role of the Numb protein in regulating cell fate. By understanding these mechanisms, it seeks to identify potential therapeutic targets for breast cancer treatment.
Stem cells (SCs) are thought to be integral to the development and progression of cancer, and their eradication may be essential for the cure of cancer.
Yet, direct proof is lacking due to our poor understanding of the molecular differences between normal and cancer SCs.
We will investigate normal and cancer mammary stem cells (MSCs) by focusing on the role of the cell fate determinant Numb in two signaling axes:
Numb:Notch and Numb:p53.
Numb is a tumor suppressor in human breast cancer.
Its exp…
IFOM-ISTITUTO FONDAZIONE DI ONCOLOGIA MOLECOLARE ETS
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
